Dexamethasone, Tocris Bioscience™

Description

Anti-inflammatory glucocorticoid

Glucocorticoid; anti-inflammatory. Reduces levels of activated NF-κB in immature dendritic cells (DCs) and inhibits differentiation into mature DCs. Induces differentiation of human mesenchymal stem cells (MSCs). Also used in the generation of liver organoids. Induces autophagy in acute lymphoblastic leukemia (ALL) cell lines.

Tocris products are for biomedical research use only. They are not intended for human or veterinary use.

Specifications

• CAS: 50-02-2
• Molecular Formula: C22H29FO5
• MDL Number: MFCD00064136
• Quantity: 100 mg
• Synonym: dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol
• InChI Key: UREBDLICKHMUKA-CXSFZGCWSA-N
• SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
• IUPAC Name: (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
• Molecular Weight (g/mol): 392.47
• PubChem CID: 5743
• ChEBI: CHEBI:41879
• Formula Weight: 392.47
• Percent Purity: >98%
• Chemical Name or Material: Dexamethasone