Diethyl bis(hydroxymethyl)malonate, 95%, Thermo Scientific Chemicals

Description

Diethyl bis(hydroxymethyl)malonate is used as a reagent for preparing 1,3-dioxanes from acetals, aldehydes and ketones. It is also used as an intermediate for the preparation of substituted malonic, acrylic and isobutyric esters, for conversion to the useful dienophiles, ?-bromomethylacrylic acid and its ethyl ester and to bis(bromomethyl)acetic acid and its methyl ester.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Diethyl bis(hydroxymethyl)malonate is used as a reagent for preparing 1,3-dioxanes from acetals, aldehydes and ketones. It is also used as an intermediate for the preparation of substituted malonic, acrylic and isobutyric esters, for conversion to the useful dienophiles, ɑ-bromomethylacrylic acid and its ethyl ester and to bis(bromomethyl)acetic acid and its methyl ester.

Solubility
Slightly soluble in water.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 20605-01-0
• Molecular Formula: C9H16O6
• Molecular Weight (g/mol): 220.221
• MDL Number: MFCD00009130
• InChI Key: WIOHBOKEUIHYIC-UHFFFAOYSA-N
• Synonym: diethyl bis hydroxymethyl malonate, diethyl 2,2-bis hydroxymethyl malonate, propanedioic acid, bis hydroxymethyl-, diethyl ester, 1,3-diethyl 2,2-bis hydroxymethyl propanedioate, diethyl 2,2-bis hydroxymethyl propanedioate, 2,2-bis hydroxymethyl malonic acid diethyl ester, bis hydroxymethyl malonic acid diethyl ester, diethyl 2,2-bis hydroxymethyl propane-1,3-dioate, acmc-20al8x, ksc490a8h
• PubChem CID: 311844
• IUPAC Name: diethyl 2,2-bis(hydroxymethyl)propanedioate
• SMILES: CCOC(=O)C(CO)(CO)C(=O)OCC

• Melting Point: 47°C to 52°C
• Flash Point: >110°C (230°F)
• Quantity: 100 g
• Beilstein: 1788515
• Solubility Information: Slightly soluble in water.
• Formula Weight: 220.22
• Percent Purity: 97%
• Chemical Name or Material: Diethyl bis(hydroxymethyl)malonate

RUO – Research Use Only