Diethyl malonate, 99%, Thermo Scientific Chemicals

Description

Diethyl malonate is used in organic synthesis for the preparation of alpha-aryl malonates, mono-substituted and di-substituted acetic acid, barbiturates and artificial flavorings. It is also involved in the synthesis of pharmaceuticals like chloroquine, butazolidin and barbital. It acts as intermediate in the synthesis of vitamin B1, vitamin B6, non-steroidal anti-inflammatory agents agrochemicals and perfumes. In Knoevenagel condensation reaction, it reacts with benzaldehyde to get diethyl benzylidenemalonate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Diethyl malonate is used in organic synthesis for the preparation of alpha-aryl malonates, mono-substituted and di-substituted acetic acid, barbiturates and artificial flavorings. It is also involved in the synthesis of pharmaceuticals like chloroquine, butazolidin and barbital. It acts as intermediate in the synthesis of vitamin B1, vitamin B6, non-steroidal anti-inflammatory agents agrochemicals and perfumes. In Knoevenagel condensation reaction, it reacts with benzaldehyde to get diethyl benzylidenemalonate.

Solubility
Miscible with ethyl alcohol, ether, chloroform and benzene. Slightly miscible with water.

Notes
Incompatible with acids, bases, oxidizing agents and reducing agents.

Specifications

Chemical Identifiers

• CAS: 105-53-3
• Molecular Formula: C7H12O4
• Molecular Weight (g/mol): 160.169
• MDL Number: MFCD00009195
• InChI Key: IYXGSMUGOJNHAZ-UHFFFAOYSA-N
• Synonym: diethyl malonate, malonic ester, propanedioic acid, diethyl ester, dicarbethoxymethane, malonic acid, diethyl ester, carbethoxyacetic ester, malonic acid diethyl ester, 1,3-diethyl propanedioate, ethyl propanedioate, ethyl malonate van
• PubChem CID: 7761
• IUPAC Name: diethyl propanedioate
• SMILES: CCOC(=O)CC(=O)OCC

• Melting Point: °C to 50°C
• Density: 1.055
• Boiling Point: 198°C to 200°C
• Flash Point: 90°C (194°F)
• Assay Percent Range: 99%
• Refractive Index: 1.414
• Quantity: 500 g
• Beilstein: 774687
• Merck Index: 14,3823
• Solubility Information: Miscible with ethyl alcohol,ether,chloroform and benzene. Slightly miscible with water.
• Formula Weight: 160.17
• Percent Purity: 99%
• Physical Form: Liquid
• Chemical Name or Material: Diethyl Malonate

RUO – Research Use Only