Dizocilpine maleate, 99+%, Thermo Scientific Chemicals

Description

NMDA receptor antagonist that prevents calcium flux

Dizocilpine maleate is used to interact at the NMDA-associated ion channel, preventing Ca2+ flux and blocking NMDA-induced depolarizations. (+)-MK 801 demonstrates potent neuroprotective effects against excitotoxic insult, showing substantial protection against neuron loss produced by NMDA and quinolinic acid introduction.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Dizocilpine maleate is used to interact at the NMDA-associated ion channel, preventing Ca2+ flux and blocking NMDA-induced depolarizations. (+)-MK 801 demonstrates potent neuroprotective effects against excitotoxic insult, showing substantial protection against neuron loss produced by NMDA and quinolinic acid introduction.

Solubility
Soluble in ethanol.

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.

Specifications

Chemical Identifiers

• CAS: 77086-22-7
• Molecular Formula: C20H19NO4
• Molecular Weight (g/mol): 337.375
• MDL Number: MFCD00082465
• InChI Key: QLTXKCWMEZIHBJ-PJGJYSAQSA-N
• Synonym: dizocilpine maleate, +-mk-801 hydrogen maleate, +-mk 801 maleate, dizocilpine hydrogen maleate, unii-6lr8c1b66q, dizocilpine maleate usan, dsstox_cid_25785, dsstox_rid_81126
• PubChem CID: 6420042
• SMILES: CC12C3=CC=CC=C3CC(N1)C4=CC=CC=C24.C(=CC(=O)O)C(=O)O

• Color: White
• Quantity: 50 mg
• Merck Index: 14,3386
• Solubility Information: Soluble in ethanol.
• Formula Weight: 337.37
• Percent Purity: ≥99%
• Physical Form: Crystalline Powder
• Chemical Name or Material: Dizocilpine maleate

RUO – Research Use Only