Drosha Monoclonal Antibody (S.12.0), Invitrogen™

Rabbit Monoclonal Antibody

Brand:  Invitrogen MA514784

Product Code. 11560401

Description

It is not recommended to aliquot this antibody.

Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003).

Specifications

• Antigen: Drosha
• Classification: Monoclonal
• Concentration: 615 μg/mL
• Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
• Gene Accession No.: Q5HZJ0, Q9NRR4
• Gene Symbols: DROSHA
• Immunogen: Synthetic peptide corresponding to residues surrounding His549 of human Drosha
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: S.12.0
• Conjugate: Unconjugated
• Gene: DROSHA
• Gene Alias: 1110013A17Rik; AI874853; Drosha; drosha ribonuclease III; drosha, double-stranded RNA-specific endoribonuclease; drosha, ribonuclease type III; ethanol induced 2; ETOHI2; HSA242976; MGC115770; nuclear RNase III Drosha; OTTHUMP00000220910; OTTHUMP00000220911; OTTHUMP00000220912; OTTHUMP00000220913; p241; Protein Drosha; putative protein p241 which interacts with transcription factor Sp1; putative ribonuclease III; RANSE3L; RGD1307626; ribonuclease 3; Ribonuclease III; ribonuclease III, nuclear; ribonuclease type III, nuclear; RN3; RNase III; RNASE3L; RNASEN
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14000, 29102
• Content And Storage: -20°C
• Form: Liquid