EAPP Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5143967

Product Code. 17990791

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

This protein may play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The C-terminal of EAPP binds the N-terminal of E2F1 and also interacts with E2F2 and E2F3, but not E2F4.

Specifications

• Antigen: EAPP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EAPP
• Gene Alias: 1810011O16Rik; BM036; BM-036; c14orf11; E2F associated phosphoprotein; E2F-associated phosphoprotein; Eapp; hypothetical protein LOC327318; RGD1309624; Unknown (protein for MGC:139672); wu:fd21g02; zgc:65820
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55837, 66266
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Isotype: IgG

• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
• Gene Accession No.: Q56P03, Q5BU09
• Gene Symbols: EAPP
• Immunogen: E.coli-derived human EAPP recombinant protein (Position: M1-S285).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Form: Lyophilized