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Tocris Bioscience™ Echistatin, alpha1 isoform

αVβ3 and glycoprotein IIb/IIIa (integrin αIIbβ3) inhibitor

Brand:  Tocris Bioscience™ 3202/100U

Product Code. 18016022

  • £331.00 / 100µg

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Description

Description

Echistatin, α1 isoform is a potent irreversible αVβ3 integrin antagonist (Ki = 0.27 nM). Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM). Prevents ADP-induced platelet aggregation via inhibition of glycoprotein IIb/IIIa (GpIIb/IIIa, αIIbβ3) receptors (IC50 = 30 nM) in vitro.
Specifications

Specifications

100 μg
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