EDAR Antibody (EDAR12), Alexa Fluor™ 488, Novus Biologicals™

Rabbit Monoclonal Antibody

Brand:  Bio-Techne NBP2-81103AF488

Product Code. 18321280

Description

EDAR Monoclonal specifically detects EDAR in Human, Mouse, Rat, Canine, Chicken samples. It is validated for Western Blot, ELISA, Immunocytochemistry/Immunofluorescence.

Specifications

• Antigen: EDAR
• Classification: Monoclonal
• Conjugate: Alexa Fluor 488
• Formulation: 50mM Sodium Borate
• Gene Symbols: EDAR
• Immunogen: EDAR12 was prepared by immunixzing female OVE1B mice (with the Edar gene deleted) subcutaneously with mouse EDAR-Fc and positive hybridoma clones were screened for binding mEDAR by ELISA.
• Quantity: 0.1 mL
• Research Discipline: Apoptosis
• Gene ID (Entrez): 10913
• Target Species: Human, Mouse, Rat, Canine, Chicken
• Form: Purified

• Applications: Western Blot, ELISA, Immunocytochemistry, Immunofluorescence
• Clone: EDAR12
• Dilution: Western Blot, ELISA, Immunocytochemistry/Immunofluorescence
• Gene Alias: Anhidrotic ectodysplasin receptor 1, DLED3, Ectodermal dysplasia receptor, ectodysplasin 1, anhidrotic receptor, ectodysplasin A receptor, Ectodysplasin-A receptor, ED1R, ED5, EDA1R, EDA3EDA-A1 receptor, EDA-A1R, Edar, FLJ94390, HRM1, mouse, homolog of, tumor necrosis factor receptor superfamily member EDAR
• Host Species: Rabbit
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: EDAR12 recognises and binds to CRD1 of the extracellular domain of mouse EDAR. EDAR3 cross-reacts with EDAR derived from human, dog, rat and chicken when EDAR is fused to the glycosylphosphatidylinositol anchor of TRAILR3. EDAR is the receptor for the TNF family ligand EDA1, which is a type II transmembrane protein possessing a collagen-like domain and a C-terminal TNF-homology domain. EDAR is important for the correct development of skin appendages including hair, teeth and eccrine sweat glands. LoF mutations in the Eda gene is known to cause XLHED (X-linked hypohidrotic ectodermal dysplasia), and results in abnormal development.
• Content And Storage: Store at 4°C in the dark.
• Isotype: IgG κ