Invitrogen™ Silencer™ Human druggable Genome siRNA Library (384 well)

The Silencer™ Human Druggable Genome siRNA Library targets genes in the known druggable genome for performing RNAi functional screens for potential therapeutic targets.

Brand:  Invitrogen™

Product Code. 15671842

Description

The Silencer Human Druggable Genome siRNA Library contains 23,349 Ambion™ Silencer siRNAs targeting 7,783 genes. This library is designed using the most up-to-date genome databases, including the NCBI RefSeq database and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC).

Why use the Silencer Human Druggable Genome siRNA Library?Silencer siRNAs are optimized for design and high quality synthesis with guaranteed silencing. The Silencer Human Druggable Genome siRNA Library contains our pre-designed and when available, validated siRNAs generated with potency and specificity in mind so you can focus on data quality. The library is delivered with full siRNA sequence information, as well as the exon targeted and each targeted gene's symbol, full name, aliases, RefSeq number, and Locus ID; plus results from any validation experiments performed using the included siRNAs. Please contact us for the complete list of targets.Silencer siRNA libraries allow you to screen efficiently and maximize data outputInvitrogen Silencer siRNAs are designed with potency in mind to ensure gene knockdown at minimum concentrations. This not only helps ensure less potential for off target effects and false positive data but also minimizes false negative outcomes of siRNA screening. The Silencer Human Druggable Genome siRNA Library contains 0.25 nmol of each siRNA, sufficient for 100 transfections (at 25 nM siRNA, 100 μL transfection volume).
Utilizing Invitrogen Silencer technology built on stringent bioinformatics to enable high target specificity and siRNA potency, the Silencer Human Druggable siRNA Library allows accurate yet cost-effective RNAi functional screening against therapeutically relevant human genes.

• Comprehensive—Expedite functional gene discovery with pre-defined Invitrogen Silencer Human Druggable siRNA Library
• Reliable—Increase target screening accuracy with three individual siRNAs per gene target.
• Effective—Reduce off target impacts at low concentrations with our proven Invitrogen Silencer siRNA design
• Convenient—Reduce data de-convolution and accelerate target validation with our 96- or 384-well arrayed format
• Customizable—Choose the best option available to meet your workflow demands, including additional siRNA scales and pooled formats

Specifications

• Description: 23,349 total siRNAs targeting 7,783 druggable genes plated onto 384-well plates (69 plates)

For research use only. Not for use in diagnostic procedures