Eotaxin Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen 500-P67BT-25UG

Product Code. 17833343

Description

AA Sequence of recombinant protein: HPGSIPTSCC FIMTSKKIPN TLLKSYKRIT NNRCTLKAIV FKTRLGKEIC ADPKKKWVQD ATKHLDQKLQ TPKP. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine Eotaxin (CCL11). Anti-Murine Eotaxin (CCL11)-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect mEotaxin by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine Eotaxin (500-P67) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant mEotaxin. Western Blot: To detect mEotaxin by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant mEotaxin is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P67BT-1MG will be provided as 2 x 500 μg

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

Specifications

• Antigen: Eotaxin
• Classification: Polyclonal
• Conjugate: Biotin
• Gene: CCL11
• Gene Alias: C-C motif chemokine 11; C-C motif chemokine ligand 11; Ccl11; chemokine (C-C motif) ligand 11; eosinophil chemotactic protein; Eotaxin; Eotaxin 1; Eotaxin1; eotaxin-1; MGC22554; Scya11; small chemokine (C-C motif) ligand 11; small inducible cytokine A11; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); small inducible cytokine subfamily A11; small-inducible cytokine A11
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20292
• Content And Storage: -20°C

• Applications: ELISA, Western Blot
• Concentration: 0.1-1.0 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P48298
• Gene Symbols: CCL11
• Immunogen: E.coli-derived Recombinant Murine Eotaxin (CCL11)
• Quantity: 25 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Form: Lyophilized