ErbB2 (HER-2), His Tag ErbB2 (HER2), His Tag Recombinant Protein

ErbB2 (HER-2), His Tag ErbB2 (HER2), His Tag Recombinant Protein

Brand:  Invitrogen PV3590

Product Code. 10083182

Description

ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.

Specifications

• Accession Number: NP_004439
• For Use With (Application): Protein Assays and Analysis, Kinase Assay
• Molecular Weight (g/mol): 68.6kDa
• Quantity: 1mg
• Regulatory Status: For research use only. Not for use in diagnostic procedures
• Gene Alias: ErbB2 (HER2), NEU
• Assays: ERBB2 (HER2) was pre-diluted in enzyme dilution buffer and assayed in 20mM Tris (pH 7.5), 5 MnCl2, 1mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2mM DTT, 0.01% CHAPS, 200μM ATP, 1000μg/mL poly [Glu, Tyr] 4:1 substrate and trace [32P]-γ-ATP for 10 minutes at 30°C
• Protein Length: Amino acids 676-1255
• Specific Reactivity: 78nmoles of phosphate transferred to poly [Glu, Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 8.33μg/mL
• Protein Tag: His Tag
• Form: Frozen

• Concentration: 0.33mg/mL
• Formulation: Frozen
• Name: ERBB2 (HER2)
• Storage Requirements: –80°C
• Packaging: 1 Each
• Common Name: ErbB2 (HER2)
• KinaseFamily: EGF receptor (ErbB)
• Product Type: ErbB2 (HER2)
• Species: Human
• Expression System: Baculovirus
• Purity or Quality Grade: 60% by SDS-PAGE

For Research Use Only. Not for use in diagnostic procedures.