Ethyl glyoxylate, ca 50% soln. in toluene, Thermo Scientific Chemicals

Description

Ethyl glyoxylate is widely used as an intermediate in the synthesis of pharmaceuticals (high reactivity of aldehyde function). It is used in the synthesis of a biodegradable polymer, poly(ethyl glyoxylate). It is actively involved in the Friedel-Crafts alkylation reactions with thiophenes to give the corresponding secondary alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl glyoxylate is widely used as an intermediate in the synthesis of pharmaceuticals (high reactivity of aldehyde function). It is used in the synthesis of a biodegradable polymer, poly(ethyl glyoxylate). It is actively involved in the Friedel-Crafts alkylation reactions with thiophenes to give the corresponding secondary alcohols.

Solubility
Immiscible with water.

Notes
Air sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Specifications

Chemical Identifiers

• CAS: 924-44-7
• Molecular Formula: C4H6O3
• Molecular Weight (g/mol): 102.089
• MDL Number: MFCD00044009
• InChI Key: DBPFRRFGLYGEJI-UHFFFAOYSA-N
• Synonym: ethyl glyoxalate, ethyl glyoxylate, ethyl oxoacetate, glyoxylic acid ethyl ester, acetic acid, oxo-, ethyl ester, ethyl glyoxalate solution, unii-ixx9mq1j1i, acetic acid, 2-oxo-, ethyl ester, ixx9mq1j1i, 2-oxoacetic acid, ethyl ester
• PubChem CID: 70211
• ChEBI: CHEBI:53275
• IUPAC Name: ethyl 2-oxoacetate
• SMILES: CCOC(=O)C=O

• Density: 1.003
• Boiling Point: 110°C
• Flash Point: 7°C (44°F)
• Refractive Index: 1.475
• Quantity: 100 g
• UN Number: UN1993
• Beilstein: 1209486
• Sensitivity: Air Sensitive
• Solubility Information: Immiscible with water.
• Formula Weight: 102.09
• Concentration or Composition (by Analyte or Components): ≈50% soln. in toluene
• Chemical Name or Material: Ethyl glyoxylate

Safety and Handling

Product Identifier

• Ethyl glyoxylate, ca 50% solution in toluene

Signal Word

• Danger

Hazard Category

• Aspiration toxicity Category 1
• Flammable liquid Category 2
• Reproductive toxicity Category 2
• Skin corrosion/irritation Category 2
• Skin sensitiser Category 1
• Specific target organ toxicity after repeated exposure Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H225-Highly flammable liquid and vapour.
• H304-May be fatal if swallowed and enters airways.
• H315-Causes skin irritation.
• H317-May cause an allergic skin reaction.
• H336-May cause drowsiness or dizziness.
• H361d-Suspected of damaging the unborn child.
• H373-May cause damage to organs.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P240-Ground/bond container and receiving equipment.
• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.

Supplemental information

• MIXTURE LIST-Contains : toluene, oxo-aceticacid

RUO – Research Use Only