Thermo Scientific™ EZ-Link™ Maleimide-PEG11-Biotin

Biotinylate reduced cysteines with this long, maleimide-activated, sulfhydryl-reactive biotinylation reagent with an 11-unit PEG spacer arm to enhance solubility and reach.

Brand:  Thermo Scientific™ 21911

Product Code. 10026073

Description

Thermo Scientific™ EZ-Link Maleimide-PEG11-Biotin is a long, maleimide-activated, sulfhydryl-reactive biotinylation reagent that includes an 11-unit polyethylene glycol spacer arm for increased water-solubility and reach.

Highlights:

• Polyethylene glycol (PEG) spacer yields biotin-labeled proteins with greater solubility and less aggregation
• Forms stable thioether bond at pH 6.5-7.5
• PEG spacer improves aqueous solubility, allowing labeling to be performed under non-denaturing, physiological conditions
• Extended spacer arm reduces steric hindrance in binding to avidin, streptavidin and Thermo Scientific NeutrAvidin Proteins

Specifications

• Product Type: Maleimide-PEG11-Biotin
• Content And Storage: Store desiccated at 4°C. Shipped at ambient temperature.
• Cell Permeability: Cell-Impermeant
• Reactive Moiety: Maleimide
• Label or Dye: Biotin
• Label Type: Biotin & Analogs

• Quantity: 25 mg
• Product Line: EZ-Link™
• Chemical Reactivity: Thiol
• Solubility: DMF (Dimethylformamide), DMSO (Dimethylsulfoxide), Water
• Spacer: Extra-long, Pegylated

Safety and Handling

Product Identifier

• EZ-Link Maleimide-PEG11-Biotin

Signal Word

• Danger

Hazard Category

• LONG-TERM AQUATIC HAZARD Chronic 3
• Carcinogenicity Category 1A
• Reproductive toxicity Category 1B
• Respiratory sensitiser Category 1
• Skin sensitiser Category 1
• Specific target organ toxicity after repeated exposure Category 2

Hazard Statement

• H317-May cause an allergic skin reaction.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
• H350-May cause cancer.
• H360D-May damage the unborn child.
• H373-May cause damage to organs.
• H412-Harmful to aquatic life with long lasting effects.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P405-Store locked up.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : sulphuric acid, nickel(II) salt

For Research Use Only. Not for use in diagnostic procedures.