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Thermo Scientific™ EZ-Link™ Maleimide-PEG11-Biotin
Biotinylate reduced cysteines with this long, maleimide-activated, sulfhydryl-reactive biotinylation reagent with an 11-unit PEG spacer arm to enhance solubility and reach.
Brand: Thermo Scientific™ 21911
Description
Thermo Scientific™ EZ-Link Maleimide-PEG11-Biotin is a long, maleimide-activated, sulfhydryl-reactive biotinylation reagent that includes an 11-unit polyethylene glycol spacer arm for increased water-solubility and reach.
Highlights:
- Polyethylene glycol (PEG) spacer yields biotin-labeled proteins with greater solubility and less aggregation
- Forms stable thioether bond at pH 6.5-7.5
- PEG spacer improves aqueous solubility, allowing labeling to be performed under non-denaturing, physiological conditions
- Extended spacer arm reduces steric hindrance in binding to avidin, streptavidin and Thermo Scientific NeutrAvidin Proteins
Specifications
Maleimide-PEG11-Biotin | |
Store desiccated at 4°C. Shipped at ambient temperature. | |
Cell-Impermeant | |
Maleimide | |
Biotin | |
Biotin & Analogs |
25 mg | |
EZ-Link™ | |
Thiol | |
DMF (Dimethylformamide), DMSO (Dimethylsulfoxide), Water | |
Extra-long, Pegylated |
Safety and Handling
- EZ-Link Maleimide-PEG11-Biotin
Signal Word
- Danger
Hazard Category
- LONG-TERM AQUATIC HAZARD Chronic 3
- Carcinogenicity Category 1A
- Reproductive toxicity Category 1B
- Respiratory sensitiser Category 1
- Skin sensitiser Category 1
- Specific target organ toxicity after repeated exposure Category 2
Hazard Statement
- H317-May cause an allergic skin reaction.
- H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
- H350-May cause cancer.
- H360D-May damage the unborn child.
- H373-May cause damage to organs.
- H412-Harmful to aquatic life with long lasting effects.
Precautionary Statement
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P260-Do not breathe dust/fume/gas/mist/vapours/spray.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
- P405-Store locked up.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Supplemental information
- MIXTURE LIST-Contains : sulphuric acid, nickel(II) salt
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For Research Use Only. Not for use in diagnostic procedures.