Fasentin, Tocris Bioscience™

Description

GLUT1/GLUT4 inhibitor; also Fas-sensitizer

GLUT1 and GLUT4 inhibitor (IC50 = 68 μM). Preferentially inhibits GLUT4 over GLUT1. Sensitizes Fas receptor in a range of tumor cell lines (IC50 = 20 μM) by modulating the extrinsic apoptotic pathway downstream of TNF receptors but upstream of effector caspases.

Specifications

Chemical Identifiers

• CAS: 392721-37-8
• Molecular Formula: C11H9ClF3NO2
• Molecular Weight (g/mol): 279.64
• MDL Number: MFCD01001285
• InChI Key: GNYIJZMBLZXJEJ-UHFFFAOYSA-N
• Synonym: Fasentin
• PubChem CID: 879520
• IUPAC Name: N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide
• SMILES: CC(=O)CC(=O)NC1=CC(=C(Cl)C=C1)C(F)(F)F

• Linear Formula: C₁₁H₉ClF₃NO₂
• Quantity: 10 mg
• Solubility Information: Soluble to 100mM in DMSO and to 100mM in ethanol
• Formula Weight: 279.64
• Percent Purity: >98%
• Physical Form: Solid
• Chemical Name or Material: N-(4-Chloro-3-(trifluoromethyl)phenyl)-3-oxobutanamide