FEN1 Monoclonal Antibody (4E7), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA123228

Product Code. 11521470

Description

Recommended positive controls: MCF7. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 a protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems.

Specifications

• Antigen: FEN1
• Classification: Monoclonal
• Concentration: 1.73 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P39748, P39749
• Gene Symbols: FEN1
• Immunogen: Recombinant human FEN-1 protein encoding amino acids 1-380 purified E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
• Clone: 4E7
• Conjugate: Unconjugated
• Gene: FEN1
• Gene Alias: AW538437; DNase IV; fen1; FEN-1; fen1 {ECO:0000255; FEN-1 {ECO:0000255; Flap endonuclease 1; flap endonuclease 1 {ECO:0000255; flap structure specific endonuclease 1; flap structure-specific endonuclease 1; flap structure-specific endonuclease 1 {ECO:0000255; HAMAP-Rule:MF_03140}; hFEN-1; Maturation factor 1; maturation factor-1; MF1; RAD2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 14156, 2237
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid