FGIN-1-27, Tocris Bioscience™

Description

Potent, specific ligand for mitochondrial DBI receptor

Binds specifically and with high affinity to the peptide DBI receptor (benzodiazepine receptor) on mitochondrial membranes, inducing production of neurosteroids, which modulate GABA receptors (EC50 = 3 nM for increase in production of pregnenolone in glial cells). Thus it reduces anxiety without causing sedation.

Specifications

Chemical Identifiers

• CAS: 142720-24-9
• Molecular Formula: C28H37FN2O
• Molecular Weight (g/mol): 436.615
• InChI Key: VUWXAQFLTSBUDB-UHFFFAOYSA-N
• Synonym: fgin-1-27, fgin 1 27, n,n-dihexyl-2-4-fluorophenyl indole-3-acetamide, fgin 1-27, n,n-di-n-hexyl-2-4-fluorophenyl indole-3-acetamide, chembl63154, 1h-indole-3-acetamide, 2-4-fluorophenyl-n,n-dihexyl, 2-2-4-fluorophenyl-1h-indol-3-yl-n,n-dihexylacetamide, tocris-0658
• PubChem CID: 132496
• IUPAC Name: 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide
• SMILES: CCCCCCN(CCCCCC)C(=O)CC1=C(NC2=CC=CC=C21)C3=CC=C(C=C3)F

• Quantity: 50 mg
• Formula Weight: 436.61
• Percent Purity: >98%
• Chemical Name or Material: FGIN-1-27