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FLASH Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA519954
This item is not returnable.
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Description
In Western blot applications, this antibody detects a band at ∽220kDa. A suggested positive control is Hela cell lysate. PA5-19954 can be used with blocking peptide PEP-0079.
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.Specifications
FLASH | |
Polyclonal | |
Unconjugated | |
CASP8AP2 | |
AA387232; CASP8 associated protein 2; CASP8AP2; CASP8-associated protein 2; caspase 8 associated protein 2; CED-4; D4Ertd659e; FLASH; FLASH homolog RIP25; FLICE associated huge; FLICE-associated huge protein; FLJ11208; human FLASH; KIAA1315; mKIAA1315; RIP25; RP11-63K6.3 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
9994 | |
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
Liquid |
Immunocytochemistry, Western Blot | |
1 mg/mL | |
PBS with 0.02% sodium azide | |
Q9UKL3 | |
CASP8AP2 | |
A synthetic peptide corresponding to amino acids near the carboxy terminus of human FLASH | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |