Tocris Bioscience™ FNIR-Tag, NHS

Near-infrared fluorescent dye for labeling of amines; supplied as NHS ester

Brand:  Tocris Bioscience™ 7373/2

Product Code. 18769296

Description

FNIR-Tag-NHS is a near-infrared fluorescent dye; supplied as an NHS ester for coupling to primary amine groups. FNIR-Tag-NHS allows a higher degree of labeling (DOL) with less aggregation than IRDye™ 800CW. When conjugated to antibodies, FNIR-Tag-NHS exhibits reduced liver uptake in vivo compared with IRDye™ 800CW conjugates. In addition, FNIR-Tag-NHS conjugates are sigificantly brighter than IRDye™ 800CW conjugates at similar labeling densities in vivo and in vitro. Antibody conjugation efficiency is greatest at pH 7.4. Excitation/emission maxima = 766/788 nm; Extinction coefficient = 200,000 M-1cm-1; QY = 0.099.

IRDye™ is a registered trademark of LI-COR Biosciences.

Specifications

• Chemical Name or Material: 2-((E)-2-((E)-2-(3-((4-((2,5-dioxopyrrolidin-1-yl)oxy)-4-oxobutyl)dimethylammonio)propoxy)-3-(2-((E)-1-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)-3,3-dimethyl-5-sulfonatoindolin-2-ylidene)ethylidene)cyclohex-1-en-1-yl)vinyl)-1-(2-(2-(2-methoxyethoxy)ethoxy)ethy
• Quantity: 2 mg
• Molecular Formula: C₅₇H₈₀N₄O₁₇S₂

• CAS: 2365033-54-9
• Target: Fluorescent Dyes
• Purity: 0.9