FPA 124, Tocris Bioscience™

Description

Akt/PKB inhibitor

Akt/PKB inhibitor (IC50 = 100 nM) that interacts with the PH and kinase domains. Inhibits cell proliferation in various cancer cell lines in vitro and decreases NF-κB activity and tumor load in vivo.

Specifications

Chemical Identifiers

• CAS: 902779-59-3
• Molecular Formula: C11H9Cl2CuN3O2S
• Molecular Weight (g/mol): 381.718
• InChI Key: HZRXQEVFXXQYFS-UHFFFAOYSA-L
• Synonym: Dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamide copper complex
• PubChem CID: 102586612
• IUPAC Name: dichlorocopper;[(4-oxochromen-3-yl)methylideneamino]thiourea
• SMILES: C1=CC=C2C(=C1)C(=O)C(=CO2)C=NNC(=S)N.Cl[Cu]Cl

• Quantity: 10 mg
• Formula Weight: 381.73
• Percent Purity: >98%
• Chemical Name or Material: FPA 124