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Tocris Bioscience™ FRAX 486
Potent PAK inhibitor; brain penetrant and orally bioavailable
£206.00
Specifications
| Purity | >98% |
|---|---|
| Product Type | FRAX 486 |
| Molecular Weight (g/mol) | 513.39 |
| Inhibitors | FRAX 486 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18711678
|
Tocris Bioscience™
5190/10 |
10 mg |
£206.00
10mg |
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Description
Potent p21-activated kinase (PAK) inhibitor (IC50 values are 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively). Blocks and reverses the DISC1 knockdown-induced reduction in dendritic spine size in cortical neurons. Attenuates dendritic spine elimination and enhances spine generation in DISC1 knockdown mice. Ameliorates autism-like behavioral symptoms in fragile X mental retardation 1 (Fmr1) knockout mice. Brain penetrant and orally bioavailable.Specifications
| >98% | |
| FRAX 486 | |
| 513.39 | |
| FRAX 486 |
For Research Use Only