Fulvestrant, MedChemExpress

MedChemExpress Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy.

Brand:  Medchem Express HY-13636

Product Code. 16406266

Description

Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy.

Specifications

• Chemical Name or Material: Fulvestrant
• Color: White
• Molecular Formula: C₃₂H₄₇F₅O₃S
• Synonym: ICI 182780 ZD 9238 ZM 182780
• SMILES: C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])[C@H](CCCCCCCCCS(CCCC(F)(F)C(F)(F)F)=O)CC4=C(C=CC(O)=C4)[C@@]3([H])CC2
• Formula Weight: 606.77
• Grade: Research
• For Use With (Application): Cancer-programmed cell death

• CAS: 129453-61-8
• Purity Grade Notes: Research
• Quantity: 100 mg
• Solubility Information: DMSO : 250 mg/mL (412.02 mM; Need ultrasonic)
• Molecular Weight (g/mol): 606.77
• Percent Purity: 95.0%
• Physical Form: Solid

Research purposes only