Tocris Bioscience™ Geldanamycin

Selective Hsp90 inhibitor

Brand:  Tocris Bioscience™ 1368/1

Product Code. 18065182

Description

Selectively inhibits heat shock protein 90 (Hsp90). Binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity. Consequently inhibits activities of oncogenic kinases (e.g. src, Raf), p53 and steroid receptors. Demonstrates antiproliferative effect on breast cancer stem-like cells.

Specifications

• Quantity: 1 mg
• Assay: >98%
• Molecular Formula: C₂₉H₄₀N₂O₉
• Solubility: Soluble to 10 mM in DMSO

• Content And Storage: Desiccate at -20°C
• CAS: 30562-34-6
• Formula Weight: 560.64g/mol