GLP1R (extracellular) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5111834

Product Code. 17199743

Description

Reconstitute antibody with 50 μL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min). Peptide sequence is: (C)KYLYEDE G(S)WTRNS Homology: Rat, mouse, human - 13/14 amino acid residues identical.

Glucagon-like peptide-1(9-36)amide and GLP-1(9-37) are the forms of GLP-1 that result from the rapid degradation of the active forms of the peptide (GLP-1(7-36)amide and GLP-1(7-37)) by the enzyme dipeptidyl peptidase-IV (DPP-IV, also known as CD26 or adenosine deaminase binding protein). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.

Specifications

• Antigen: GLP1R (extracellular)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Glp1r
• Gene Alias: GCG; Glicentin; Glip; GLP1; GLP-1; GLP-1 receptor; GLP1R; GLP-1R; GLP-1-R; GLP1Rc; GLP2; GLP-2; GLP-I receptor; Glpr; Glucagon-like peptide 1 receptor; GRPP; RATGL1RCP
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14652, 25051, 2740
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunomicroscopy, Western Blot
• Concentration: 0.8 mg/mL
• Formulation: PBS with 1% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O35659, P32301, P43220
• Gene Symbols: Glp1r
• Immunogen: Peptide corresponding to amino acid residues 288-301 of rat GLP1R (2ndextracellular loop)
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG