Cytiva HiScreen™ Capto™ S, Capto™ Q and Capto™ DEAE Prepacked IEX Columns

Designed for method optimization and parameter screening

Product Code	Brand	Product Type	Ligand Type	pH Range
10609620	Cytiva 28-9269-78	HiScreen Capto Q IEX column	Quaternary Amine	2 to 12
10619620	Cytiva 28-9269-79	HiScreen Capto S IEX column	Sulphonate group	4 to 12
10352780	Cytiva 28-9269-82	HiScreen Capto DEAE IEX Column	Diethylaminoethyl	2 to 9

Description

• Fast, efficient, and cost-effective capture and intermediate protein purification
• Ready-to-use columns for convenient process development optimization
• Highly cross-linked agarose with dextran surface extender matrix
• Bed height of 10cm is designed to allow method optimization and parameter screening
• Easily connected in series to achieve 20cm bed height
• Small bed volume (4.7mL) gives fast result and minimal sample/buffer consumption
• Combines high capacity with high flow velocity and low backpressure to reduce process cycle times and increase productivity
• Reproducible results, scalable to BioProcess columns packed with the same chromatography media using the same linear fluid velocity

Capto S: Strong cation (sulfonate group) exchange BioProcess™ medium
Capto Q: Strong anion (quartenary amine group) exchange BioProcess medium
Capto DEAE: Weak anion (diethylaminoethyl group) exchange BioProcess medium

Specifications

• Buffer: 1M Acetic Acid, 1M NaOH, 8M Urea, 6M Guanidine Hydrochloride, 30% Isopropanol and 70% Ethanol
• Diameter (English) Inner: 0.3 in.
• Quantity: 1 x 4.7mL
• Height (Metric): 100mm
• Material: Polypropylene
• Particle Size: 45 to 165μm
• Content And Storage: 4° to 30°C
• For Use With (Application): Modern large-scale manufacturers for fast, efficient and cost-effective capture and intermediate Protein purification, optimization and parameter screening

• Bed Volume: 4.7mL
• Diameter (Metric) Inner: 7.7mm
• Height (English): 3.93 in.
• Flow Rate: <700 cm/hr.
• Max. Pressure: 3 bar
• Support Type: Highly cross-linked Agarose with Dextran surface extender
• Column Type: Ion Exchange Column

Safety and Handling

Product Identifier

• HiScreen Capto Q

Signal Word

• Warning

Hazard Category

• Flammable liquid Category 3

Hazard Statement

• H226-Flammable liquid and vapour.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P241-Use explosion-proof electrical/ventilating/lighting/ equipment.
• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : ethanol
• UNKNOWN ACUTE-16.5 per cent of the mixture consists of component(s) of unknown acute toxicity.