HLA-ABC Monoclonal Antibody (2G5), FITC, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA181300

Product Code. 11559982

Description

For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Mouse anti Mouse MHC Class I antibody, clone 2G5 recognizes a monomorphic epitope present on murine MHC class I molecules, expressed at varying levels on the majority of nucleated cells.

HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumor defense. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Specifications

• Antigen: HLA-ABC
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 1% BSA and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P01889, P04439, P10321
• Gene Symbols: HLA-A, HLA-B, HLA-C, LOC100515902
• Immunogen: Purified H-2Kb and H-2Db MHC-I molecules.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Bovine, Guinea Pig, Hamster, Human, Mouse, Ovine, Porcine, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry
• Clone: 2G5
• Conjugate: FITC
• Gene: HLA-C
• Gene Alias: A29 protein, alpha chain of MHC class II, antigen presenting molecule, AS, Aw-33, Aw-74, B-4901, B-5001, Bw-47, Bw-50, class I MHC, HLA-B antigen, D6S204, epididymis secretory protein Li 83, H-2K, H2-K, H-2K(d), HEL-S-83, histocompatibility antigen, HLA A, HLA -B, HLA B-40011, HLA B44, HLA C, HLA class I antigen, HLA class I antigen HLA-B, HLA class I histocompatibility antigen C alpha chain, HLA class I histocompatibility antigen Cw-1 alpha chain, HLA class I histocompatibility antigen, A alpha chain, HLA class I histocompatibility antigen, A-1 alpha chain, HLA class I histocompatibility antigen, A-11 alpha chain-like, HLA class I histocompatibility antigen, A-30 alpha chain, HLA class I histocompatibility antigen, A-33 alpha chain, HLA class I histocompatibility antigen, A-74 alpha chain, HLA class I histocompatibility antigen, B alpha chain, HLA class I histocompatibility antigen, B-47 alpha chain, HLA class I histocompatibility antigen, B-50 alpha chain, HLA class I histocompatibil
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100515902, 3105, 3106, 3107
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
• Form: Liquid