HSP60 Monoclonal Antibody (3G8), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA515836

Product Code. 12897852

Description

MA5-15836 targets HSP60 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples. The MA5-15836 immunogen is purified recombinant fragment of human HSP60 expressed in E. Coli. . MA5-15836 detects HSP60 which has a predicted molecular weight of approximately 61kDa.

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.

Specifications

• Antigen: HSP60
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: P10809, P63038, P63039
• Gene Symbols: HSPD1
• Immunogen: Purified recombinant fragment of human HSP60 expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 15510, 3329, 63868
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
• Clone: 3G8
• Conjugate: Unconjugated
• Gene: HSPD1
• Gene Alias: 60 kDa chaperonin; 60 kDa heat shock protein; 60 kDa heat shock protein, mitochondrial; 60kDa; Chaperonin 60; CPN60; GROEL; heat shock 60kD protein 1 (chaperonin); heat shock 60kDa protein 1; heat shock 60kDa protein 1 (chaperonin); Heat shock protein; heat shock protein 1 (chaperonin); heat shock protein 60; heat shock protein 60 (liver); heat shock protein 65; heat shock protein family D (Hsp60) member 1; heat shock protein, 60 kDa; HLD4; HSP; Hsp60; HSP-60; Hsp60s1; HSP65; HSP-65; Hspd1; Hspd1-30p; HuCHA60; hypothetical protein; I79_011398; mitochondrial matrix protein P1; P1 protein; P60 lymphocyte protein; RCJMB04_7g5; short heat shock protein 60 Hsp60s1; SPG13; Unknown (protein for IMAGE:7943409)
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Non-human Primate, Rat
• Product Type: Antibody
• Isotype: IgG1