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HTR1B Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA533293
Code : NEW
Additional Details : Weight : 0.01000kg
Description
Serotonin (5-hydroxytryptamine, 5-HT), originally discovered as a serum factor plays important roles in regulating diverse biological processes in central and peripheral nervous systems, cardiovascular systems, and gastrointestinal systems. Molecular cloning studies have identified 5 receptors belonging to the 5-HT1 subtypes. These receptors are negatively coupled to adenylyl cyclase. Radioligand binding studies suggest the presence of 5-HT1B (formerly known as 5-HT1DbR) sites in substantia nigra, dorsal subiculum, globus pallidus, and superior collicum. In situ hybridization studies show abundance of 5-HT1BR mRNA in CA1 pyramidal cells of hippocampus, Purkinje cells of cerebellum, olfactory tubercle, subthalamic nucleus and somewhat lower levels in the caudate-putamen, cortical areas, thalamic and hypothalamic nuclei.Specifications
HTR1B | |
Polyclonal | |
Unconjugated | |
HTR1B | |
5-HT<1B> receptor; 5ht1b; 5-HT1B; 5-HT-1B; 5HT1B Receptor; 5-HT1B receptor; 5-HT1B serotonin receptor; 5-HT1DB; 5-HT-1D-beta; 5-hydroxytryptamine (serotonin ) receptor 1B; 5-hydroxytryptamine (serotonin) receptor 1B; 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled; 5-hydroxytryptamine receptor 1B; HTR1B; HTR1D2; HTR1DB; S12; serotonin (5-hydroxytryptamine (5HT)) receptor type 1B; serotonin 1D beta receptor; Serotonin receptor 1B | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
100009594, 100689321, 100717602, 15551, 25075, 317707, 3351, 397563 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin) | |
1 mg/mL | |
PBS with 0.1% sodium azide | |
O08892, P28222, P28334, P28564, P46636, P49144, P79399 | |
HTR1B | |
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human 5HT1B Receptor. | |
50 μg | |
Primary | |
Bovine, Guinea Pig, Hamster, Human, Mouse, Porcine, Rabbit, Rat | |
Antibody | |
IgG |