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Gibco™ Human Amphiregulin Recombinant Protein, PeproTech®
E. coli Recombinant Protein
£64.75 - £1200.00
Specifications
| Accession Number | P15514 |
|---|---|
| For Use With (Application) | ELISA, Functional Assay, Western Blot |
| Formulation | protein with no preservative |
| Gene ID (Entrez) | 374 |
| Molecular Weight (g/mol) | 11.3 |
| Código de producto | Marca | Quantity | Precio | Cantidad y disponibilidad | |||||
|---|---|---|---|---|---|---|---|---|---|
| Código de producto | Marca | Quantity | Precio | Cantidad y disponibilidad | |||||
|
17830103
|
Gibco™
100-55B-100UG |
100 μg |
£240.00
100µg |
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|
17810183
|
Gibco™
100-55B-10UG |
10 μg |
£64.75
10µg |
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|
17820563
|
Gibco™
100-55B-1MG |
1 mg |
£1200.00
1mg |
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|
17849892
|
Gibco™
100-55B-250UG |
250 μg |
£421.00
250µg |
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|
17801253
|
Gibco™
100-55B-500UG |
500 μg |
£720.00
500µg |
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|
17880763
|
Gibco™
100-55B-50UG |
50 μg |
£157.00
50µg |
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Descripción
Amphiregulin (AR) binds to EGF-Receptor (EGFR) with lower affinity than EGF. The mature secreted form AR is an 84-amino acid residue glycosylated polypeptide growth regulator, which is generated by proteolytic processing of a 252-amino acid transmembrane precursor. Seven different polypeptide ligands, which derive from distinct genes, are capable of binding to the extracellular domain of EGFR. These ligands include EGF, TGFalpha, AR, HB-EGF, cripto-1, epiregulin, and betacellulin. All of these growth factors contain a characteristic EGF-like domain which is defined by 6 evenly spaced cysteine residues that generate 3 loops through the formation of disulfide bonds. AR protein has been localized by immunohistochemistry to the epithelium of the colon, stomach, pancreas, breast, and placenta. AR is reportedly overexpressed in human cancers of breast, colon, stomach, and pancreas.Especificaciones
| P15514 | |
| protein with no preservative | |
| 11.3 | |
| E. coli | |
| RUO | |
| amphiregulin; amphiregulin B; AR; AREG; AREGB; colorectum cell-derived growth factor; CRDGF; Mcub; MGC13647; schwannoma-derived growth factor; SDGF | |
| Human | |
| Recombinant | |
| Lyophilized |
| ELISA, Functional Assay, Western Blot | |
| 374 | |
| Human Amphiregulin | |
| -20°C | |
| <1 EU/μg | |
| AREG | |
| Unconjugated | |
| SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR KKKNPCNAEF QNFCIHGECK YIEHLEAVTC KCQQEYFGER CGEKSMKTHS MIDSSLSK | |
| ≥ 95% by SDS-PAGE gel and HPLC analyses. |