Invitrogen™ Human CD200 His-tag, Recombinant Protein

HEK293 cells Recombinant Protein

Brand:  Invitrogen™ A42571

Product Code. 17194233

Description

CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.

Specifications

• Accession Number: P41217
• Formulation: PBS with 0.02% Tween 80, 5% mannitol, 5% trehalose and no preservative
• Name: Human CD200 His-tag
• Source: HEK293 cells
• Regulatory Status: RUO
• Gene Alias: antigen identified by monoclonal antibody MRC OX-2; CD200; CD200 antigen; CD200 molecule; cell surface protein (thymocyte antigen identified by monoclonal antibody MRC-O x 2); Cspmo2; MO x 1; MO x 2; MRC; MRC OX-2 antigen; MRCO x 2; My033; O x 2; OX-2; OX-2 membrane glycoprotein
• Specific Reactivity: Human
• Recombinant: Recombinant
• Purity or Quality Grade: ≥ 90%

• For Use With (Application): Control, ELISA, Immunohistochemistry, Western Blot
• Gene ID (Entrez): 4345
• Quantity: 50 μg
• Storage Requirements: -20°C
• Endotoxin Concentration: <1 EU/μg
• Gene Symbol: Cd200
• Conjugate: Unconjugated
• Form: Lyophilized