Gibco™ Human EPO (Erythropoietin) Recombinant Protein, PeproTech®

CHO cells Recombinant Protein

Product Code	Brand	Quantity
17830773	Gibco™ 100-64-100UG	100 μg
17831643	Gibco™ 100-64-10UG	10 μg
17810463	Gibco™ 100-64-1MG	1 mg
17871643	Gibco™ 100-64-250UG	250 μg
17850553	Gibco™ 100-64-500UG	500 μg
17801043	Gibco™ 100-64-50UG	50 μg

Description

Erythropoietin (EPO) protein is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. EPO is not responsible for early commitment to the lineage, and instead induces the final maturation of partially differentiated erythroid cells and the production of red cell-specific proteins, such as hemoglobin. The EPO receptor (EPOR) is present in higher levels on precursor cells, and expression diminishes with cell maturation.Hepatocytes are the main source of EPO in the fetus, followed by interstitial cells of the kidney after birth and through adulthood. EPO expression is upregulated during hypoxia, and low levels of transcription have also been detected in lung and brain tissue under these conditions. Recent data suggest that EPO may also play a role in the protection of neuronal tissue from damage and initiation of repair.

Specifications

• Accession Number: P01588
• Formulation: protein with no preservative
• Molecular Weight (g/mol): 18.4
• Source: CHO cells
• Regulatory Status: RUO
• Gene Alias: EP; EPO; Epoetin; erythropoietin; MGC138142; MVCD2
• Specific Reactivity: Human
• Recombinant: Recombinant
• Form: Lyophilized

• For Use With (Application): ELISA, Functional Assay, Western Blot
• Gene ID (Entrez): 2056
• Name: Human EPO (Erythropoietin)
• Storage Requirements: -20°C
• Endotoxin Concentration: <1 EU/μg
• Gene Symbol: EPO
• Conjugate: Unconjugated
• Sequence: APPRLICDSR VLERYLLEAK EAENITTGCA EHCSLNENIT VPDTKVNFYA WKRMEVGQQA VEVWQGLALL SEAVLRGQAL LVNSSQPWEP LQLHVDKAVS GLRSLTTLLR ALGAQKEAIS PPDAASAAPL RTITADTFRK LFRVYSNFLR GKLKLYTGEA CRTGDR
• Purity or Quality Grade: ≥ 90% by SDS-PAGE gel and HPLC analyses.