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Invitrogen™ Human HEXA ELISA Kit
Human HEXA quantitates human HEXA in serum, plasma, supernatant.
Brand: Invitrogen™ EH241RBX5
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Description
Human HEXA quantitates human HEXA in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human HEXA.
This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Specifications
| Beta-hexosaminidase subunit alpha; beta-N-acetylhexosaminidase subunit alpha; EC 3.2.1; EC 3.2.1.52; Hex-1; HEXA; hexosaminidase A; hexosaminidase A (alpha polypeptide); hexosaminidase subunit A; hexosaminidase subunit alpha; Hexose aminidase A (alpha polypeptide); MGC99608; N-acetyl-beta-glucosaminidase subunit alpha; TSD | |
| 0.082 ng/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| HEXA | |
| <10% | |
| HRP | |
| Research Use Only | |
| 2°C to 8°C | |
| 1 hr 20 min |
| 0.082 to 20 ng/mL | |
| Biotin | |
| Plasma, Serum, Supernatant | |
| P06865 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| 5 x 96 Tests | |
| Supernatant, 50 μL; Plasma, 50 μL; Serum, 50 μL | |
| HEXA | |
| 4 hr 45 min |