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Invitrogen™ Human IL-34 (Carrier-Free) Recombinant Protein, eBioscience™
Recombinant Protein
£85.25 - £182.00
Specifications
Accession Number | Q6ZMJ4 |
---|---|
Formulation | 0.02M citric acid with no preservative; pH 3.0 |
Gene ID (Entrez) | 146433 |
Molecular Weight (g/mol) | 52.5kDa |
Name | Human IL-34 Carrier-Free |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15528816
|
Invitrogen™
34-8684-61 |
2μg |
£85.25
2µg |
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15538816
|
Invitrogen™
34-8684-63 |
10μg |
£182.00
10µg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen. Description: IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen. Applications Reported: Recombinant human IL-34 is biologically active and can induce MCP-1 secretion by normal human peripheral blood cells. Applications Tested: The activity of this protein was determined by measuring MCP-1 secretion from normal human peripheral blood cells. Source: HEK293 cells (amino acids Asn21-Pro242; accession # NP_001166243); contains a C-terminal 8X His tag. Bioactivity: The activity of this protein was determined by measuring MCP-1 secretion from normal human peripheral blood cells. Endotoxin: Less than 0.1ng/ug cytokine as determined by the LAL assay. Purity: >95% as determined by SDS-PAGE and HPLC. Molecular Weight: 52.5 kDa. Storage and handling: For best recovery, quick spin vial prior to opening. Use in sterile environment. Reconstitute in water to a concentration of 0.1-1.0mg/mL. Do not vortex. Store lyophilized protein at less than or equal to -20°C. Reconstituted protein solution can be stored with carrier protein (e.g., 0.1% BSA) at less than or equal to -20°C.Specifications
Q6ZMJ4 | |
146433 | |
Human IL-34 Carrier-Free | |
SDS-PAGE and HPLC | |
RUO | |
Less than 0.1ng/μg cytokine as determined by the LAL assay | |
IL34 | |
Recombinant Protein, Carrier-Free | |
Unconjugated | |
Human (HEK293) | |
Lyophilized | |
Affinity chromatography |
0.02M citric acid with no preservative; pH 3.0 | |
52.5kDa | |
3.0 | |
-20°C | |
HEK 293 cells (amino acids Asn21-Pro242; Accession # NP_001166243); contains a C-terminal 8X His tag | |
Human IL-34 Carrier-Free | |
The activity of this protein was determined by measuring MCP-1 secretion from normal human peripheral blood cells. | |
Human | |
Hu | |
Recombinant | |
Recombinant |
Safety and Handling
missing translation for 'shelfLife' : 12 Months