Invitrogen™ Human IL-8 (CXCL8) (1-77), Recombinant Protein

Recombinant Protein

Brand:  Invitrogen™ 14-8089-63

Product Code. 15537496

Description

Human IL-8, also called neutrophil attractant/activating protein (NAP-1), monocyte derived neutrophil activating peptide (MONAP), monocyte derived neutrophil activating factor (ANF), monocyte derived neutrophil chemotactic factor (MDNCF), and neutophil activating factor (NAF), is a ∽6-8 kDa factor produced by variety types of cells including monocytes, lymphocytes, granulocytes, fibroblasts and endothelial cells. IL-8 is an inflammatory cytokine which functions as a neutrophil chemoatractant and activating factor. It also attracts basophils and a subpopulation of lymphocytes.

Specifications

• Accession Number: NM_000584
• Formulation: Sterile liquid; phosphate buffered saline, pH 7.2, 1.0% BSA. 0.22μm filtered.
• Name: IL-8
• Quantity: 10μg
• Storage Requirements: Store at less than or equal to -70°C.
• Structural Form: E. coli expressed amino acids Ser 28-Ser 99 of human IL-8 accession # NM_000584
• Gene Symbol: Interleukin-8, IL8, 72aa
• Product Type: Recombinant Protein
• Cross Reactivity: Human
• Purity or Quality Grade: >98%

• For Use With (Application): Cytokine Bioassay
• Molecular Weight (g/mol): The protein is not methionylated at the N-terminal and has a predicted molecular mass of 8,386. The DTT reduced protein migrates as an 8kDa polypeptide and the non-reduced polypeptide migrates as a 9kDa polypeptide on SDS-PAGE.
• Purification Method: SDS-PAGE
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: Less than 0.01ng/μg cytokine as determined by the LAL assay.
• Biological Activity: Measured by chemotaxis assay of human peripheral blood neutrophils. Maximal chemoattractant activity was observed between 10-100ng/mL.
• Conjugate: Unconjugated
• Recombinant: Recombinant