Gibco™ Human MIP-3 (CCL23) Recombinant Protein, PeproTech®

E. coli Recombinant Protein

Brand:  Gibco™ 300-29-250UG

Product Code. 17852893

Description

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms.

Specifications

• Accession Number: P55773
• Formulation: protein with no preservative
• Molecular Weight (g/mol): 11.3
• Quantity: 250 μg
• Storage Requirements: -20°C
• Endotoxin Concentration: <1 EU/μg
• Gene Symbol: CCL23
• Conjugate: Unconjugated
• Sequence: RVTKDAETEF MMSKLPLENP VLLDRFHATS ADCCISYTPR SIPCSLLESY FETNSECSKP GVIFLTKKGR RFCANPSDKQ VQVCMRMLKL DTRIKTRKN
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.

• For Use With (Application): ELISA, Functional Assay, Western Blot
• Gene ID (Entrez): 6368
• Name: Human MIP-3 (CCL23)
• Source: E. coli
• Regulatory Status: RUO
• Gene Alias: C6 beta-chemokine; C-C motif chemokine 23; C-C motif chemokine ligand 23; CCL23; CCL23(19-99); CCL23(22-99); CCL23(27-99); CCL23(30-99); chemokine (C-C motif) ligand 23; Ck beta 8-1; CKb8; CKB-8; Ckb-8-1; CK-BETA-8; hmrp-2 A; Macrophage inflammatory protein 3; MIP3; MIP-3; MIP-3 CK-BETA-8; MPIF1; MPIF-1; MPIF-1 Ckb-8-1; Myeloid progenitor inhibitory factor 1; SCYA23; small inducible cytokine subfamily A (Cys-Cys), member 23; Small-inducible cytokine A23
• Specific Reactivity: Human
• Recombinant: Recombinant
• Form: Lyophilized