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Gibco™ Human Neurturin Recombinant Protein, PeproTech®
E. coli Recombinant Protein
£65.00 - £2410.00
Specifications
Accession Number | Q99748 |
---|---|
For Use With (Application) | ELISA, Functional Assay, Western Blot |
Formulation | protein with no preservative |
Gene ID (Entrez) | 4902 |
Molecular Weight (g/mol) | 23.6 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17834613
|
Gibco™
450-11-100UG |
100 μg |
£482.00
100µg |
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17834723
|
Gibco™
450-11-1MG |
2 x 500 μg |
£2410.00
1mg |
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17814013
|
Gibco™
450-11-20UG |
20 μg |
£158.00
20µg |
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17804313
|
Gibco™
450-11-250UG |
250 μg |
£842.00
250µg |
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17854753
|
Gibco™
450-11-500UG |
500 μg |
£1442.00
500µg |
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17824313
|
Gibco™
450-11-5UG |
5 μg |
£65.00
5µg |
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Description
Glial cell line-derived neurotrophic factor (GDNF) plays key roles in the control of vertebrate neuron survival and differentiation. A novel neurotrophic factor was recently cloned from human and mouse and designated neurturin. Physiological responses to neurturin (NTN) require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNRalpha. The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently and termed GDNFR-b, Ret ligand 2 (RETL2) or TGF-beta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFR-a-2 recently. NTN binds to and forms a complex with GFR-a-2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway. Both NTN and GDNF can activate the MAP kinase and phosphatidylinositol 3-kinase pathways and play a critical role in the development of many neuronal populations. Neurturin and GDNF define a new family of neurotrophic factors.Specifications
Q99748 | |
protein with no preservative | |
23.6 | |
E. coli | |
RUO | |
neurturin; NRTN; NTN; prepro-neurturin | |
Human | |
Recombinant | |
Lyophilized |
ELISA, Functional Assay, Western Blot | |
4902 | |
Human Neurturin | |
-20°C | |
<1 EU/μg | |
NRTN | |
Unconjugated | |
ARLGARPCGL RELEVRVSEL GLGYASDETV LFRYCAGACE AAARVYDLGL RRLRQRRRLR RERVRAQPCC RPTAYEDEVS FLDAHSRYHT VHELSARECA CV | |
≥ 98% by SDS-PAGE gel and HPLC analyses. |