Gibco™ Human Oncostatin M (227 aa) Recombinant Protein, PeproTech®

E. coli Recombinant Protein

Product Code	Brand	Quantity
17881603	Gibco™ 300-10-100UG	100 μg
17891003	Gibco™ 300-10-10UG	10 μg
17820243	Gibco™ 300-10-1MG	1 mg
17871203	Gibco™ 300-10-250UG	250 μg
17800633	Gibco™ 300-10-2UG	2 μg
17861713	Gibco™ 300-10-500UG	500 μg
17831603	Gibco™ 300-10-50UG	50 μg

Description

Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF.

Specifications

• Accession Number: P13725
• Formulation: protein with no preservative
• Molecular Weight (g/mol): 25.7
• Source: E. coli
• Regulatory Status: RUO
• Gene Alias: MGC20461; OncoM; oncostatin M; oncostatin-M; OSM
• Specific Reactivity: Human
• Recombinant: Recombinant
• Form: Lyophilized

• For Use With (Application): ELISA, Functional Assay, Western Blot
• Gene ID (Entrez): 5008
• Name: Human Oncostatin M (227 aa)
• Storage Requirements: -20°C
• Endotoxin Concentration: <1 EU/μg
• Gene Symbol: OSM
• Conjugate: Unconjugated
• Sequence: AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRRHSPH QALRKGVRRT RPSRKGKRLM TRGQLPR
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.