Invitrogen™ Human TGF-beta 1 Recombinant Protein

Recombinant Human Transforming Growth Factor β 1 (TGFB1) is a bioactive protein intended for use in cell culture applications. TGFB1 is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types.

Brand:  Invitrogen™ PHG9214

Product Code. 10355488

Description

Human TGF-beta 1 Recombinant Protein for Western Blot, IHC, ELISA, Ctrl, FN

TGFB1 acts synergistically with TGF-α in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB1 activation and signaling may result in apoptosis.

• High purity—no interference from other proteins or contaminants
• High biological activity—more results with less protein
• Proven compatibility—Gibco™ proteins bioassayed with Gibco™ media

High Purity Recombinant Bioactive Protein
Recombinant Human Transforming Growth Factor β 1 is one of more than 250 Gibco™ recombinant proteins. To help ensure Gibco™ growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco™ Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Transforming Growth Factor β 1 (TGFB1) specific activity is determined by measuring the TGFB1 dose-dependent inhibition of proliferation of mouse HT-2 cells stimulated with mouse IL-4.

Proven Compatibility
Gibco™ proteins are bioassayed with Gibco™ media. Since 1962, Gibco™ has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

Specifications

• For Use With (Application): Cell Culture
• Purification Method: Sequential Chromatography
• Gene Alias: TGF-β1
• Biological Activity: ED₅₀ = ≤ 0.2 ng⁄mL
• Content And Storage: Store this lyophilized preparation at 2-8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤–20°C. Avoid repeated freeze⁄thaw cycles.
• Mass: 10 μg
• Expression System: Mammalian
• Protein Form: Recombinant, Ligand
• Protein Subtype: TGFs (Transforming Growth Factors)
• Product Line: Gibco™

• Molecular Weight (g/mol): 25 kDa
• Quantity: 10 μg
• Protein Length: 112 aa (2 identical)
• Species: Human
• Endotoxin Level: < 0.1 ng/μg
• Shipping Condition: Wet Ice
• Protein Family: Growth Factors & Receptors
• Form: Lyophilized
• Research Category: Immunology, Neurobiology, Oncology, Stem Cell Research, Cardiovascular Research, Differentiation, Bone Research