Thermo Scientific™ Hypersil™ PREP BDS C8 HPLC Columns

Product Code	Brand	Length (Metric)	Diameter (Metric)	Particle Size	Column Format
16358916	Thermo Scientific™ 40103-052130	50 mm	2 mm	3 μm	Preparative Column, Standard
16368916	Thermo Scientific™ 40103-054630	50 mm	4.6 mm	3 μm	Preparative Column, Standard
16378916	Thermo Scientific™ 40103-102130	100 mm	2 mm	3 μm	Preparative Column, Standard
16388916	Thermo Scientific™ 40103-104630	100 mm	4.6 mm	3 μm	Preparative Column, Standard
16398916	Thermo Scientific™ 40103-152130	150 mm	2 mm	3 μm	Preparative Column, Standard
16308926	Thermo Scientific™ 40103-154630	150 mm	4.6 mm	3 μm	Preparative Column, Standard
16318926	Thermo Scientific™ 40103-252130	250 mm	2 mm	3 μm	Preparative Column, Standard
16328926	Thermo Scientific™ 40103-254630	250 mm	4.6 mm	3 μm	Preparative Column, Standard
16338926	Thermo Scientific™ 40105-052130	50 mm	2 mm	5 μm	Preparative Column, Standard
16348926	Thermo Scientific™ 40105-054630	50 mm	4.6 mm	5 μm	Preparative Column, Standard
16358926	Thermo Scientific™ 40105-059070A	50 mm	10 mm	5 μm	Preparative Column, Standard
16368926	Thermo Scientific™ 40105-059270A	50 mm	20 mm	5 μm	Preparative Column, Standard
16378926	Thermo Scientific™ 40105-059270XL	50 mm	25 mm	5 μm	Preparative Column, Xtended Life
16388926	Thermo Scientific™ 40105-102130	100 mm	2 mm	5 μm	Preparative Column, Standard
16398926	Thermo Scientific™ 40105-104630	100 mm	4.6 mm	5 μm	Preparative Column, Standard
16308936	Thermo Scientific™ 40105-109070A	100 mm	10 mm	5 μm	Preparative Column, Standard
16318936	Thermo Scientific™ 40105-109270A	100 mm	20 mm	5 μm	Preparative Column, Standard
16328936	Thermo Scientific™ 40105-109270XL	100 mm	25 mm	5 μm	Preparative Column, Xtended Life
16338936	Thermo Scientific™ 40105-152130	150 mm	2 mm	5 μm	Preparative Column, Standard
16348936	Thermo Scientific™ 40105-154630	150 mm	4.6 mm	5 μm	Preparative Column, Standard
16358936	Thermo Scientific™ 40105-159070A	150 mm	10 mm	5 μm	Preparative Column, Standard
16368936	Thermo Scientific™ 40105-159270A	150 mm	20 mm	5 μm	Preparative Column, Standard
16378936	Thermo Scientific™ 40105-159270XL	150 mm	25 mm	5 μm	Preparative Column, Xtended Life
16388936	Thermo Scientific™ 40105-159370A	150 mm	30 mm	5 μm	Preparative Column, Standard
16398936	Thermo Scientific™ 40105-159370XL	150 mm	30 mm	5 μm	Preparative Column, Xtended Life
16308946	Thermo Scientific™ 40105-159570A	150 mm	50 mm	5 μm	Preparative Column, Standard
16318946	Thermo Scientific™ 40105-159570XL	150 mm	50 mm	5 μm	Preparative Column, Xtended Life
16328946	Thermo Scientific™ 40105-252130	250 mm	2 mm	5 μm	Preparative Column, Standard
16338946	Thermo Scientific™ 40105-254630	250 mm	4.6 mm	5 μm	Preparative Column, Standard
16348946	Thermo Scientific™ 40105-259070A	250 mm	10 mm	5 μm	Preparative Column, Standard
16358946	Thermo Scientific™ 40105-259270A	250 mm	20 mm	5 μm	Preparative Column, Standard
16368946	Thermo Scientific™ 40105-259270XL	250 mm	25 mm	5 μm	Preparative Column, Xtended Life
16378946	Thermo Scientific™ 40105-259370A	250 mm	30 mm	5 μm	Preparative Column, Standard
16388946	Thermo Scientific™ 40105-259370XL	250 mm	30 mm	5 μm	Preparative Column, Xtended Life
16398946	Thermo Scientific™ 40105-259570A	250 mm	50 mm	5 μm	Preparative Column, Standard
16308956	Thermo Scientific™ 40105-259570XL	250 mm	50 mm	5 μm	Preparative Column, Xtended Life
16318956	Thermo Scientific™ 40110-018823A	8 mm	10 mm	10 μm	Guard Column
16328956	Thermo Scientific™ 40110-019023A	20 mm	10 mm	10 μm	Guard Column
16338956	Thermo Scientific™ 40110-019323A	30 mm	10 mm	10 μm	Guard 1/16 in.
16348956	Thermo Scientific™ 40110-019323B	30 mm	10 mm	10 μm	Guard 1/8 in.
16358956	Thermo Scientific™ 40110-029023A	20 mm	20 mm	10 μm	Guard Column
16368956	Thermo Scientific™ 40110-029323A	30 mm	20 mm	10 μm	Guard 1/16 in.
16378956	Thermo Scientific™ 40110-029323B	30 mm	20 mm	10 μm	Guard 1/8 in.
16388956	Thermo Scientific™ 40110-059070A	50 mm	10 mm	10 μm	Preparative Column, Standard
16398956	Thermo Scientific™ 40110-059270A	50 mm	20 mm	10 μm	Preparative Column, Standard
16308966	Thermo Scientific™ 40110-059270XL	50 mm	25 mm	10 μm	Preparative Column, Xtended Life
16318966	Thermo Scientific™ 40110-109070A	100 mm	10 mm	10 μm	Preparative Column, Standard
16328966	Thermo Scientific™ 40110-109270A	100 mm	20 mm	10 μm	Preparative Column, Standard
16338966	Thermo Scientific™ 40110-109270XL	100 mm	25 mm	10 μm	Preparative Column, Xtended Life
16348966	Thermo Scientific™ 40110-159070A	150 mm	10 mm	10 μm	Preparative Column, Standard
16358966	Thermo Scientific™ 40110-159270A	150 mm	20 mm	10 μm	Preparative Column, Standard
16368966	Thermo Scientific™ 40110-159270XL	150 mm	25 mm	10 μm	Preparative Column, Xtended Life
16378966	Thermo Scientific™ 40110-159370A	150 mm	30 mm	10 μm	Preparative Column, Standard
16388966	Thermo Scientific™ 40110-159370XL	150 mm	30 mm	10 μm	Preparative Column, Xtended Life
16398966	Thermo Scientific™ 40110-159570A	150 mm	50 mm	10 μm	Preparative Column, Standard
16308976	Thermo Scientific™ 40110-159570XL	150 mm	50 mm	10 μm	Preparative Column, Xtended Life
16318976	Thermo Scientific™ 40110-259070A	250 mm	10 mm	10 μm	Preparative Column, Standard
16328976	Thermo Scientific™ 40110-259270A	250 mm	20 mm	10 μm	Preparative Column, Standard
16338976	Thermo Scientific™ 40110-259270XL	250 mm	25 mm	10 μm	Preparative Column, Xtended Life
16348976	Thermo Scientific™ 40110-259370A	250 mm	30 mm	10 μm	Preparative Column, Standard
16358976	Thermo Scientific™ 40110-259370XL	250 mm	30 mm	10 μm	Preparative Column, Xtended Life
16368976	Thermo Scientific™ 40110-259570A	250 mm	50 mm	10 μm	Preparative Column, Standard
16378976	Thermo Scientific™ 40110-259570XL	250 mm	50 mm	10 μm	Preparative Column, Xtended Life

Description

Scale up from analytical to a preparative LC method with Thermo Scientific™ Hypersil™ PREP BDS C8 reversed phase preparative HPLC column. Our columns come in a variety of dimensions including an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed. With similar selectivity to C18 columns and predictable elution order, C8 columns with base deactivation for reduced silanol activity are ideal for analytes with medium hydrophobicity or when a less hydrophobic phase is required to obtain optimum retention. The lower hydrophobicity allows compounds to elute more quickly, yielding faster separations.

Similar selectivity, less retention than C18 columns

• Successful retention and separation of moderately hydrophobic analytes.
• Ideal for fatty acids, which are too hydrophobic for analysis using C18 columns.
• Base deactivated silica.
• C8 (USP L7) selectivity.
• pH stable from 2 to 8.
• Maximum temperature of 60°C.

Faster separations

• Higher analytical throughput compared to C18 alkyl chain chemistry.
• Quicker compound elution due to reduced hydrophobic interactions.

Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.

Standard Threaded and Standard Flange Hardware

• Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
• Standard threaded hardware for column i.d. < 40mm.
• Standard flange hardware for column i.d. ≥ 40mm.
• Standard hardware can be modified on request to be compatible with SFC.

XtendedLife Hardware

• Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly.
• Compatible with SFC and is available in dimensions up to 50mm i.d.

Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.

Customer Specific Orders

• If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in a preparative scale not shown or would like to discuss a specific column dimension, we would be happy to discuss your requirements.
• Please contact your local sales representative for Customer Specific Orders.
• Custom built columns are not eligible for returns.

Specifications

• pH: 2 to 8
• Surface Area: 185 m²/g
• USP Type: L7
• Packing Material: Spherical, Fully Porous, Base-Deactivated Silica
• Column Type: Reversed Phase
• Phase: Reversed Phase

• Pore Size: 145 Å
• Temperature: 60°C
• Stationary Phase: C8
• Carbon Load: 7%
• Endcapped: Yes