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Invitrogen™ I-TAC/CXCL11 Mouse ELISA Kit
Sandwich ELISA Kit
£504.00 - £4370.00
Specifications
Accession Number | Q9JHH5 |
---|---|
Assay Sensitivity | 6 pg/mL |
Assay | Solid-phase sandwich ELISA |
Conjugate | Biotin |
Product Type | ELISA Kit |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15435253
|
Invitrogen™
EMCXCL11 |
96 Tests |
£504.00
1 set |
Estimated Shipment: 18-10-2024
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17155709
|
Invitrogen™
EMCXCL11X5 |
5 x 96 Tests |
£2320.00
Each |
Estimated Shipment: 25-10-2024
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|||||
18537884
|
Invitrogen™
EMCXCL11X10 |
10 x 96 Tests |
£4370.00
Pack of 10 |
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Description
The Mouse I-TAC/CXCL11 ELISA quantitates Ms I-TAC in mouse serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Ms I-TAC. Principle of the method The Mouse I-TAC solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen. Rigorous validation Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
Interferon-inducible T-cell alpha chemoattractant ( I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate. Its molecular weight is 8-11 kD. I-TAC is also known as CXCL-11 and IP-9. The cytokine is involved in regulating calcium release and inducing a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia and in patients with multiple sclerosis.Specifications
Q9JHH5 | |
Solid-phase sandwich ELISA | |
ELISA Kit | |
This ELISA kit shows no cross-reactivity with the following cytokines tested: Mouse CD30, L CD30, T CD40, CRG-2, CTACK, CXCL16, Eotaxin , Eotaxin-2, Fas Ligand, Fractalkine, GCSF, GM-CFS, IFN- gamma, IGFBP-3, IGFBP-5, IGFBP-6, IL-1 alpha, IL-1 beta, IL-2, IL-3, IL-3 Rb, IL-4, IL-5, IL-9, IL-10, IL-12 p40/p70, IL-12 p70, IL-13, IL-17, KC, Leptin R, LEPTIN(OB), LIX, L-Selectin, Lymphotactin, MCP-1, MCP- 5, M-CSF, MIG, MIP-1 alpha, MIP-1 gamma, MIP-2, MIP-3 beta, MIP-3 alpha, PF-4, PSelectin, RANTES, SCF, SDF-1 alpha, TARC, TCA-3, TECK, TIMP-1, TNF-alpha, TNF RI, TNF RII, TPO, VCAM-1, VEGF. | |
ELISA, Protein Assays, Protein Biology, Cancer Biology, Immunology, Neuroscience, Neurobiology, Protein Detection, Protein Analysis | |
56066 | |
<12% | |
HRP | |
Inflammation | |
Cxc11, H174, I-tac, Ip9, Itac, Scyb11, Scyb9b, b-R1, betaR1 | |
1 hr. 20 min. |
6 pg/mL | |
Biotin | |
Chemokine & Receptors | |
Mouse | |
Colorimetric Microplate Reader | |
Cxcl11 | |
<10% | |
RUO | |
2°C to 8°C | |
Mouse | |
4 hr. 45 min. |