Ibuprofen, 99%, Thermo Scientific Chemicals

Description

Ibuprofen, 2-4-isobutylphenyl propanoic acid, CAS # 15687-27-1, is a laboratory form of the over-the-counter nonsteroidal anti-inflammatory (NSAID) drug.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• Ibuprofen (2-4-isobutylphenyl propanoic acid) is a common NSAID that reduces pyrogen release and inflammation
• Ibuprofen is a racemic mixture that consists of an R-enantiomer and S-enantiomer; the S-enantiomer is proposed to be the stronger acting agent
• It is a propionic acid derivative, a short-chain saturated fatty acid bound to ethane
• Ibuprofen inhibits cyclooxygenases and reduces prostaglandin formation, inhibiting fever and pain

Applications

• Ibuprofen reduces both local and systemic inflammation; suitable for use in vitro or in vivo to study specific or broad mechanisms
• Intended for sensitive biochemical applications such as HPLC

Specifications

Chemical Identifiers

• CAS: 15687-27-1
• Molecular Formula: C13H18O2
• Molecular Weight (g/mol): 206.29
• MDL Number: MFCD00010393
• InChI Key: HEFNNWSXXWATRW-UHFFFAOYNA-N
• PubChem CID: 3672
• ChEBI: CHEBI:5855
• IUPAC Name: 2-[4-(2-methylpropyl)phenyl]propanoic acid
• SMILES: CC(C)CC1=CC=C(C=C1)C(C)C(O)=O

• Melting Point: 75.0°C to 78.0°C
• Color: White
• Boiling Point: 157.0°C (4.0 mmHg)
• Infrared Spectrum: Authentic
• Assay Percent Range: 99%
• Packaging: Glass bottle
• Linear Formula: (CH₃)₂CHCH₂C₆H₄CH(CH₃)COOH
• Quantity: 10 g
• Merck Index: 15,4919
• Synonym: ibuprofen, 2-4-isobutylphenyl propanoic acid, motrin, brufen, nurofen, advil, dolgit, liptan, nuprin, anflagen
• Solubility Information: Solubility in water: insoluble. Other solubilities: readily soluble in most organic solvents
• Formula Weight: 206.27
• Percent Purity: 99%
• Physical Form: Crystalline Powder
• Chemical Name or Material: Ibuprofen

Safety and Handling

Product Identifier

• Ibuprofen

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.
• H302-Harmful if swallowed.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

RUO – Research Use Only