Thermo Scientific™ IDEIA™ Lyme Neuroborreliosis Kit

Detect the human IgG and IgM antibodies to Borrelia burgdorferi in the diagnosis of Lyme neuroborreliosis with this enzyme immunoassay.

Marke:  Thermo Scientific™ K602811-2

Artikelnummer. 13276059

Beschreibung

Detect the intrathecally produced human IgG and IgM antibodies to Borrelia burgdorferi with Thermo Scientific™ IDEIA™ Lyme Neuroborreliosis Kit. The enzyme immunoassay is designed to deliver rapid detection of human intrathecal IgG and IgM antibodies to Borrelia burgdorferi sensu lato as an aid in the diagnosis of Lyme neuroborreliosis.

Lyme borreliosis is a multisystem infection caused by the tickborne spirochete Borrelia burgdorferi sensu lato. Involvement of the nervous system, neuroborreliosis is a common and serious manifestation of Lyme borreliosis. Neuroborreliosis develops in approximately 10% of patients who have not received treatment for the primary stage lesion. A sensitive and reliable diagnostic test for neuroborreliosis is needed as a number of other diseases with similar symptoms exist and, in contrast to these diseases, neuroborreliosis can be treated with antibiotics.

Use IDEIA Lyme Neuroborreliosis Kit for differential diagnosis of Lyme neuroborreliosis from other potential causes of similar symptoms.

• Simple—ready-to-use liquid reagents and concentrates make the assay easy to implement and run
• Excellent sensitivity and specificity—high quality, well characterized antibodies used in the assay provide excellent sensitivity and specificity
• Easy-to-read results

The assay uses purified, native B. afzelii strain DK1 flagellum as test antigen. The flagellum is highly immunogenic, elicits an early, strong and persistent immune response^1,2 , and is the major antigen for the intrathecal antibody response^3,4. Compared with the conventional antigen, which is based on whole cell extract of the spirochete, the purified, native flagellar antigen improves the diagnostic sensitivity and specificity of serological assays for Lyme neuroborreliosis^5,6. Furthermore, the use of flagellum as test antigen is appropriate in all geographical areas as the flagellum shows no significant variation between B. burgdorferi strains.

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Spezifikation

• Content And Storage: 2°C to 8°C
• Detectable Analytes: B. burgdorferi IgG, IgM
• Includes: Microtitration plate, sample diluent, wash buffer, IgG positive control, IgM negative control, flagellum conjugate, reconstitution buffer, peroxidase complex, substrate TMB, stop solution, instruction booklet

• Description: IDEIA™ Lyme Neuroborreliosis Enzyme Immunoassay
• Type: Borrelia Testing Kit
• Quantity: 48 Tests

Sicherheit und Handhabung

Signalwort

• Danger

Gefahrenkategorie

• Reproductive toxicity Category 1B

Gefahrenhinweis

• H360D-May damage the unborn child.

Sicherheitshinweis

• P201-Obtain special instructions before use.
• P202-Do not handle until all safety precautions have been read and understood.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P308+P313-IF exposed or concerned: Get medical advice/attention.