Iduronate 2 Sulfatase Monoclonal Antibody (OTI1D9), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA525855

Product Code. 15955454

Description

Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.

Specifications

• Antigen: Iduronate 2 Sulfatase
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P22304, Q08890
• Gene Symbols: Ids
• Immunogen: Full length human recombinant protein of IDS produced in HEK293T cell
• Quantity: 100μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1D9
• Conjugate: Unconjugated
• Gene: Ids
• Gene Alias: alpha-L-iduronate sulfate sulfatase; AW214631; Ids; Iduronate 2-sulfatase; iduronate 2-sulfatase (Hunter syndrome); iduronate 2-sulfatase 14 kDa chain; Iduronate 2-sulfatase 42 kDa chain; iduronate sulfatase; iduronate-2-sulfatase; idursulfase; MPS2; SIDS
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15931, 3423
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid