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IL-2 Polyclonal Antibody, Biotin, eBioscience™, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen 13-7028-81
Description
Description: The rabbit anti-human IL-2 polyclonal antibody reacts with human interleukin-2 (IL-2), a 17 kDa T cell growth factor and a major immunoregulatory cytokine. Applications Reported: This polyclonal antibody has been reported for use in detection of human IL-2 by ELISA. Applications Tested: The biotinylated polyclonal rabbit anti-human IL-2 antibody has been tested as the detection antibody in a sandwich ELISA for analysis of human IL-2 in combination with the purified MQ1-17H12 (14-7029) antibody for capture and recombinant human IL-2 (14-8029) as the standard. A suitable range of concentrations of this antibody for ELISA detection is 0.5-2 μg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 1000 pg/mL - 8 pg/mL should be included in each ELISA plate. Filtration: 0.2 μm post-manufacturing filtered.
Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an μgcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.Specifications
IL-2 | |
Polyclonal | |
Biotin | |
IL2 | |
aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF | |
Rabbit | |
50 μg | |
Primary | |
Human | |
Antibody | |
IgG |
ELISA | |
0.5 mg/mL | |
PBS with 0.09% sodium azide; pH 7.2 | |
P60568 | |
IL2 | |
Affinity chromatography | |
RUO | |
3558 | |
4° C, do not freeze | |
Liquid |
For Research Use Only.