Iodoacetic acid, 97+%, Thermo Scientific Chemicals

Description

Iodoacetic acid is used as a reagent for the modification of sulfhydryl groups in organic synthesis. It reacts with cysteine moiety in proteins to prevent the re-formation of disulfide bonds during protein sequencing. It is also used as a general reagent in acylation reactions as well as in glycopeptide synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Iodoacetic acid is used as a reagent for the modification of sulfhydryl groups in organic synthesis. It reacts with cysteine moiety in proteins to prevent the re-formation of disulfide bonds during protein sequencing. It is also used as a general reagent in acylation reactions as well as in glycopeptide synthesis.

Solubility
Soluble in water, alcohol and ethanol. Slightly soluble in ether and chloroform.

Notes
Light sensitive. Store in cool place. Incompatible with strong oxidizing agents, bases and strong reducing agents.

Specifications

Chemical Identifiers

• CAS: 64-69-7
• Molecular Formula: C2H3IO2
• Molecular Weight (g/mol): 185.948
• MDL Number: MFCD00002685
• InChI Key: JDNTWHVOXJZDSN-UHFFFAOYSA-N
• Synonym: iodoacetic acid, acetic acid, iodo, iodoacetate, monoiodoacetic acid, monoiodoacetate, monoiodine acetate, iodoaceticacid, iodoethanoic acid, acetic acid, 2-iodo, kyselina jodoctova
• PubChem CID: 5240
• ChEBI: CHEBI:74571
• IUPAC Name: 2-iodoacetic acid
• SMILES: C(C(=O)O)I

• Melting Point: 79°C to 82°C
• Boiling Point: 208°C (decomposition)
• Odor: Pungent
• Quantity: 25 g
• UN Number: UN2923
• Beilstein: 1739079
• Sensitivity: Light sensitive
• Merck Index: 14,5025
• Solubility Information: Soluble in water,alcohol and ethanol. Slightly soluble in ether and chloroform.
• Formula Weight: 185.95
• Percent Purity: ≥97%
• Chemical Name or Material: Iodoacetic acid

Safety and Handling

Product Identifier

• Iodoacetic acid

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 1 A

Hazard Statement

• H301-Toxic if swallowed.
• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : Iodoacetic acid

RUO – Research Use Only