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Thermo Scientific Chemicals Ionomycin, 96% Product Code.: 15414829

Thermo Scientific Chemicals Ionomycin, 96%

Product Code. 15414829
1 mg
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Quantity:
1 mg
5 mg
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Product Code. 15414829

Brand: Thermo Scientific Chemicals J62448.M^

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This item is not returnable. View return policy

Highly selective and potent calcium ionophore

Ionomycin free acid is a beneficial tool in research to raise intracellular calcium levels. Also this antibiotic can be used to study the calcium transport across the plasma membrane. It has been shown to induce central demyelination , inhibit adrenal bovine TREK-1 channels , and to regulate cell division of mature human B cells . It is used to study the effects of calcium flux on endoplasmic reticulum (ER) stress, mitochondrial stress and intrinsic apoptosis mechanisms. It is also used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2, and IL-4 usually in conjunction with PMA.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 56092-81-0
Molecular Formula C41H72O9

Specifications

Quantity 1 mg
Description Colorless
Content And Storage -30°C to -10°C
For Use With (Application) Highly selective and potent calcium ionophore
Formula Weight 709.02
Odor Alcohol-like
Product Type Ionomycin
Form Solution in ethanol
Beilstein 3642126
InChI Key PGHMRUGBZOYCAA-OJFQOPKISA-N
SMILES C[C@H](CCC(O)=O)C[C@H](C)C[C@H](C)C(=O)\C=C(/O)[C@H](C)C[C@H](C)C\C=C\[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)CC1CC[C@](C)(O1)C1CC[C@](C)(O1)[C@@H](C)O
IUPAC Name (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-22-[(2S,5'S)-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl-[2,2'-bioxolan]-5-yl]-4,6,8,12,14,18,20-heptamethyl-9-oxodocosa-10,16-dienoic acid
Molecular Weight (g/mol) 709.02
Assay 98%
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Certificates

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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberN07L039 Certificate TypeCertificate of Analysis Date10/02/2025 Catalog NumberJ62448.#0,J62448.M^
Lot NumberM21L047 Certificate TypeCertificate of Analysis Date28/01/2025 Catalog NumberJ62448.#0,J62448.M^
Lot NumberU20K017 Certificate TypeCertificate of Analysis Date11/09/2024 Catalog NumberJ62448.#0,J62448.M^
Lot NumberS06K016 Certificate TypeCertificate of Analysis Date18/06/2024 Catalog NumberJ62448.#0,J62448.M^
Lot NumberP21K026 Certificate TypeCertificate of Analysis Date02/04/2024 Catalog NumberJ62448.#0,J62448.M^
compliance-icons compliance-icons
Product Identifier
  • Ionomycin
Signal Word
  • Danger
Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Flammable liquid Category 2
Hazard Statement
  • H225-Highly flammable liquid and vapour.
  • H319-Causes serious eye irritation.
Precautionary Statement
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P264-Wash face, hands and anyexposed skin thoroughly after handling.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
Supplemental information
  • MIXTURE LIST-Contains : ethanol, ionomycin

RUO – Research Use Only

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