Isopropyl isocyanate, 98+%, Thermo Scientific Chemicals

Description

 

Isopropyl isocyanate is used as a reagent in the preparation of androgen receptor antagonist for prostate cancer treatment. It is also used in the synthesis of selective dual inhibitor of mammalian target of rapamycin (mTORC1 and mTORC2). Further, it serves as a reagent in the synthesis of O-aryl N-isopropylcarbamates. In addition to this, it is used as a derivatization reagent during the stereoisomeric analysis of secondary alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Isopropyl isocyanate is used as a reagent in the preparation of androgen receptor antagonist for prostate cancer treatment. It is also used in the synthesis of selective dual inhibitor of mammalian target of rapamycin (mTORC1 and mT

Specifications

• CAS: 1795-48-8
• Density: 0.868
• Boiling Point: 74°C to 75°C
• Flash Point: −3°C (26°F)
• Odor: Acrid
• Molecular Formula: C4H7NO
• Refractive Index: 1.384
• MDL Number: MFCD00002037
• Quantity: 1 g
• UN Number: UN2483
• Beilstein: 969356
• Sensitivity: Moisture sensitive
• Synonym: isopropyl isocyanate, propane, 2-isocyanato, isopropylisocyanate, isocyanic acid isopropyl ester, iso-propyl isocyanate, isocyanic acid, isopropyl ester, isopropylisocynate, isoproylisocyanate, 2-propylisocyanate, isoproyl isocyanate
• Solubility Information: Immiscible with water.
• InChI Key: GSLTVFIVJMCNBH-UHFFFAOYSA-N
• SMILES: CC(C)N=C=O
• IUPAC Name: 2-isocyanatopropane
• Molecular Weight (g/mol): 85.11
• PubChem CID: 61277
• Formula Weight: 85.11
• Percent Purity: ≥98%
• Chemical Name or Material: Isopropyl isocyanate

Safety and Handling

Product Identifier

• Isopropyl isocyanate

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 1
• Acute toxicity Category 3
• Serious eye damage/eye irritation Category 2
• Flammable liquid Category 2
• Respiratory sensitiser Category 1
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H225-Highly flammable liquid and vapour.
• H301-Toxic if swallowed.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H330-Fatal if inhaled.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
• H335-May cause respiratory irritation.
• EUH014-Reacts violently with water.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : Isocyanate disopropyle

RUO – Research Use Only