Isopropyltriphenylphosphonium iodide, 98+%, Thermo Scientific Chemicals

Description

Useful precursor of isopropylidene unit by Wittig reaction with aldehydes. It is also used in tandem cyclopropanation and Wittig olefination in a synthesis of chrysanthemic acid. Also employed in Wittig and cyclopropanation reactions. It is used as a reactant for total synthesis of heliananes, in the preparation of highly substituted benzene derivatives, synthesis of curcuphenol and elvirol analogs via a retro-aldol reaction as fungicidal agents, 4-substituted methoxylbenzoyl-aryl-thiazoles analogues as potent and orally bioavailable anticancer agents.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Useful precursor of isopropylidene unit by Wittig reaction with aldehydes. It is also used in tandem cyclopropanation and Wittig olefination in a synthesis of chrysanthemic acid. Also employed in Wittig and cyclopropanation reactions. It is used as a reactant for total synthesis of heliananes, in the preparation of highly substituted benzene derivatives, synthesis of curcuphenol and elvirol analogs via a retro-aldol reaction as fungicidal agents, 4-substituted methoxylbenzoyl-aryl-thiazoles analogues as potent and orally bioavailable anticancer agents.

Solubility
Solubility in methanol, very faint turbidity.

Notes
Light sensitive and hygroscopic. Store away from oxidizing agents and light. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 24470-78-8
• Molecular Formula: C21H22IP
• Molecular Weight (g/mol): 432.29
• MDL Number: MFCD00031595
• InChI Key: HHBXWXJLQYJJBW-UHFFFAOYSA-M
• Synonym: isopropyltriphenylphosphonium iodide, phosphonium, 1-methylethyl triphenyl-, iodide, isopropyltriphenylphosphanium iodide, isopropyl triphenyl phosphonium iodide, triphenyl propan-2-yl phosphanium iodide, i-propyl triphenylphosphonium iodide, isopropyl triphenylphosphonium iodide, acmc-209gck, ksc493k7j, isopropyltriphenylphosphine iodide
• PubChem CID: 2723783
• IUPAC Name: triphenyl(propan-2-yl)phosphanium;iodide
• SMILES: [I-].CC(C)[P+](C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1

• Melting Point: 195°C to 198°C
• Quantity: 10 g
• Beilstein: 3599629
• Sensitivity: Hygroscopic; Light sensitive
• Formula Weight: 432.29
• Percent Purity: ≥98%
• Chemical Name or Material: Isopropyltriphenylphosphonium iodide

Safety and Handling

Product Identifier

• Isopropyltriphenylphosphonium iodide

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Precautionary Statement

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Supplemental information

• MIXTURE LIST-Contains : Isopropyltriphenylphosphonium iodide

RUO – Research Use Only