missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Phenylacetamides
  8. 18055012

J 104129 fumarate, Tocris Bioscience™

Product Code. 18055012
Click to view available options
Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective M3 antagonist

Potent M3 muscarinic receptor antagonist that displays ∽ 120-fold selectivity over M2 receptors (Ki values are 4.2, 19 and 490 nM for human M3, M1 and M2 receptors respectively). Exhibits > 250-fold bronchial selectivity; inhibits ACh-induced bronchoconstriction but not ACh-induced bradycardia (KB values are 3.3 and 170 nM for rat trachea M3 and rat right atria M2 receptors respectively).

Specifications

CAS 257603-40-0
Molecular Formula C28H40N2O6
Quantity 10 mg
Synonym j 104129 fumarate, j104129 fumarate hplc, ?r-?-cyclopentyl-?-hydroxy-n-1-4-methyl-3-pentenyl-4-piperidinyl benzeneacetamide fumarate, alphar-alpha-cyclopentyl-alpha-hydroxy-n-1-4-methyl-3-pentenyl-4-piperidinyl benzeneacetam
InChI Key HUCQUCITPHOUAC-DSSYAJFBSA-N
SMILES CC(=CCCN1CCC(CC1)NC(=O)C(C2CCCC2)(C3=CC=CC=C3)O)C.C(=CC(=O)O)C(=O)O
IUPAC Name (E)-but-2-enedioic acid;(2R)-2-cyclopentyl-2-hydroxy-N-[1-(4-methylpent-3-enyl)piperidin-4-yl]-2-phenylacetamide
Molecular Weight (g/mol) 500.636
PubChem CID 56972189
Formula Weight 500.63
Percent Purity >99%
Chemical Name or Material J 104129 fumarate
Show More Show Less
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.