Tocris Bioscience™ JTE 013

S1P2 receptor antagonist

Brand:  Tocris Bioscience™ 2392/10

Product Code. 18736957

Description

JTE 013 is a sphingosine-1-phosphate (S1P) receptor antagonist, highly selective for S1P2 (EDG-5). Inhibits S1P binding to human S1P2 receptors with an IC50 value of 17.6 nM. At concentrations up to 10 μM, displays 4.2% inhibition of S1P3 and does not antagonize S1P1. Enhances S1P-induced angiogenesis in vivo.

Specifications

• Purity: >98%
• Product Type: JTE 013
• Inhibitors: JTE 013

• Quantity: 10 mg
• Molecular Weight (g/mol): 408.29

For Research Use Only