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Tocris Bioscience™ JTE 013
S1P2 receptor antagonist
Brand: Tocris Bioscience™ 2392/10
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Description
JTE 013 is a sphingosine-1-phosphate (S1P) receptor antagonist, highly selective for S1P2 (EDG-5). Inhibits S1P binding to human S1P2 receptors with an IC50 value of 17.6 nM. At concentrations up to 10 μM, displays 4.2% inhibition of S1P3 and does not antagonize S1P1. Enhances S1P-induced angiogenesis in vivo.Specifications
>98% | |
JTE 013 | |
JTE 013 |
10 mg | |
408.29 |
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