Tocris Bioscience™ KYL

EphA4 kinase inhibitor; neuroprotective

Brand:  Tocris Bioscience™ 5290/1

Product Code. 18768088

Description

KYL is an EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective.

Specifications

• Description: KYL
• Product Type: KYL
• Sequence: Lys-Tyr-Leu-Pro-Tyr-Trp-Pro-Val-Leu-Ser-Ser-Leu

• Molecular Weight (g/mol): 1465.75
• Quantity: 1 mg

For Research Use Only